There are a few ways to change eyes color in Photoshop. The first way is to use the eyedropper tool. To change the color of one eye, click on the eye and then drag the cursor over the desired color. The second way is to use the Hue/Saturation tool. To change the color of one eye, click on the eye and then drag the cursor over the desired hue or saturation. The third way is to use a layer mask. To change the color of one eye, click on a layer mask and then drag and drop it onto another layer or document.